This probably isn't what you're looking for, OP, but in most books, movies and TV shows about high school, the pretty, popular kids are usually the bad guys and the ugly, unpopular kids are usually the good guys (of course, they're very rarely truely ugly). I've never seen one of those where the protagonist was beautiful and the antagonist was ugly, unless they were going for a "nerd who is actually a jerk/creep/pervert" thing, which happens often enough in real life.