I did feel unnerved. Similar to F.E.A.R and Fallout 3, Bioshock made me feel isolated and slightly afraid of what was around every corner. But honestly? Just think of it as though you have to get from point A to point B and just kill everything inbetween. Have all the lights on, play music in the background. Just give it a go! It's too much of a good game to miss out on.