case: (Default)
Case ([personal profile] case) wrote in [community profile] fandomsecrets2012-01-06 07:18 pm

[ SECRET POST #1830 ]


⌈ Secret Post #1830 ⌋

Warning: Some secrets are NOT worksafe and may contain SPOILERS.

01.


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02.
[Masterchef Australia]


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03.
[Grimm]


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04.
[Cracked.com]


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05.
[Stargate Universe]


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06.
[Skulduggery Pleasant]


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07.
[Young Justice]


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08.
[Chobits]


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09.
[Sailor Moon, Howard Stern]


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10.
[The Wonder Years/How I Met Your Mother]


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11.
[Community]


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12.
[Homestuck]


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13.
[Nutcracker, Motion Picture]


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14.
[David Archuleta]


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15.
[Love Actually]


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16.


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17.
[itskingsleybitch]


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18. [repeat]


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19.
[FFVII]


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20.
[Shake it Up/Bones]


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21.
[Sherlock Series 1]


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22.
[Pokemon]


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23. [repeat]


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24.
[Hatoful Boyfriend]


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25.
[Wonder Woman]


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26.
[James Deen]


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27.
[The Iron Giant]


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28.
[Code Geass]


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29.
[Code Geass]


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30.
[Code Geass]


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31.
[Code Geass]


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[ ----- SPOILERY SECRETS AHEAD ----- ]










32. [SPOILERS for Dead Rising 2: Off The Record]



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33. [SPOILERS for Skyrim]



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[ ----- TRIGGERY SECRETS AHEAD ----- ]














34. [TRIGGER WARNING for rape]



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35. [TRIGGER WARNING for mentions of rape]



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36. [TRIGGER WARNING for rape]



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37. [TRIGGER WARNING for rape]



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Notes:

Secrets Left to Post: 00 pages, 000 secrets from Secret Submission Post #261.
Secrets Not Posted: [ 0 - broken links ], [ 0 - not!secrets ], [ 0 - not!fandom ], [ 0 - too big ], [ 0 - repeat ].
Current Secret Submissions Post: here.
Suggestions, comments, and concerns should go here.

[identity profile] bluejessie.livejournal.com 2012-01-07 02:59 am (UTC)(link)
I'm annoyed by the poor wording in that quote, as it seems to imply that a parent with a gene will definitely pass it on to their child. This is incorrect. There is a great reference here about ALS, and the genetics of it: http://www.ncbi.nlm.nih.gov/books/NBK1450/. Hopefully the information in there is not too technical.

The gist is, only 10% of ALS cases are thought to be familial. (And of those cases, there are multiple gene mutations on different chromosomes that cause the disorder, though SOD1 on chromosome 21 appears to be the most common.) Apart from rare juvenile disorders, these are inherited in a dominant pattern, meaning even if your father was in the 10% of patients with a familial disorder, you would only have a 50% chance of inheriting that gene. (Your father had two chromosomes, and only one had the mutation. It's random chance which one you received.)

I'm sorry for your loss. Hopefully this information will help you feel a bit better about your personal health situation. If you continue to have concerns, consider talking to your doctor and getting a referral to a genetic counsellor. They can discuss if there are any testing options available to you.